白介素32抗体
规格：1mg/1ml
英文名： IL32
别名： Interleukin-32/Natural killer cells protein 4; IL32; IL-32; IL 32; IL-32alpha; IL-32beta; IL-32delta; IL-32gamma; natural killer transcript 4; NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; tumor necrosis fac
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IL-32
交叉反应：Human,
细胞定位：分泌型蛋白
白介素32抗体产品介绍：background: Interleukin 32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2. It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32. IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. As treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-alpha, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFN-gamma, it has been suggested that IL-32 may play a role in autoimmune白介素32抗体 and inflammatory diseases such as rheumatoid arthritis. Function: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and 白介素32抗体p38 MAPK. Subcellular Location: Secreted. Tissue Specificity: Selectively expressed in lymphocytes. Expression is more prominent in immune cells than in non-immune cells. Gene ID: 9235 Database links: Entrez Gene: 9235 Human Omim: 606001 Human SwissProt: P24001 Human Unigene: 943 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. IL-32是近年来发现的一种炎性细胞因子，主要由T**细胞、NK细胞、单核细胞和上皮细胞等产生。IL-32诱导细胞因子的产生，在自身**方面起重要作用。<
白介素32抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 **学 激酶和磷酸酶 细胞表面分子 自然杀伤细胞 t-**细胞 上皮细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid