白细胞介素28B抗体
规格：1mg/1ml
英文名： IL28B
别名： Interleukin-28B; IL28B; IFNL3; IL-28B; IL28C; interferon, lambda 3; interferon, lambda 4; interleukin 28C; IL-28C; IFN-lambda-3; IFN-lambda-4; IFNL4; interleukin-28C; cytokine Zcyto22; interferon lamb
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from humna IL-28B
交叉反应：Human,
细胞定位：
白细胞介素28B抗体产品介绍：background: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A(IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq]. Function: Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed 白细胞介素28B抗体of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Subcellular Location: Secreted. Similarity: Belongs to the白细胞介素28B抗体 lambda interferon family. Gene ID: 282617 Database links: Entrez Gene: 282617 Human Omim: 607402 Human SwissProt: Q8IZI9 Human Unigene: 406744 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
白细胞介素28B抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞表面分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid