白介素-17F抗体
规格：1mg/1ml
英文名： IL17F
别名： IL-17F; C49A; FISP; IL 24; IL 4 induced secreted protein; IL-24; IL10B; Il24; IL17F_HUMAN; interleukin 24; Interleukin-24; MDA-7; MDA7; Melanocyte associated Mda 7; Melanoma differentiation associatio
分子量： 17kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IL-17F
交叉反应：Human,
细胞定位：分泌型蛋白
产品介绍：background: The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated 白介素-17F抗体T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008] Function: Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis. Subunit: Homodimer; disulfide-linked. Subcellular Location: Secreted. Tissue Specificity: Expressed in activated, but not resting, CD4+ T白介素-17F抗体-cells and activated monocytes. DISEASE: Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6) [MIM:613956]. CANDF6 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly白介素-17F抗体 Candida albicans. Similarity: Belongs to the IL-17 family. Gene ID: 112744 Database links: Entrez Gene: 112744 Human Omim: 606496 Human SwissProt: Q96PD4 Human Unigene: 272295 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
白介素-17F抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞表面分子 t-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid