DNA损伤结合蛋白1抗体
规格：1mg/1ml
英文名： DDB1
别名： DNA damage-binding protein 1; DDB1; DDB-1; ;Damage specific DNA binding protein 1; DDB 1; DDB p127 subunit; DDBa; DNA damage binding protein 1; UV damaged DNA binding factor; UV damaged DNA binding pr
分子量： 125kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DDB1
交叉反应：Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit,
细胞定位：细胞核 细胞浆
DNA损伤结合蛋白1抗体产品介绍：background: This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. DNA损伤结合蛋白1抗体[provided by RefSeq]. Subunit: Component of the UV-DDB complex which includes DDB1 and DDB2. Subcellular Location: Cytoplasm. Nucleus. Note=Primarily cytoplasmic. Translocates to the nucleus following UV irradiation and subsequently accumulates at sites of DNA damage. Similarity: Belongs to the DDB1 family. Gene ID: 1642 Database links: Entrez Gene: 511951 Cow Entrez Gene: 100290337 Human DNA损伤结合蛋白1抗体Entrez Gene: 1642 Human Entrez Gene: 13194 Mouse Entrez Gene: 64470 Rat Omim: 600045 Human SwissProt: A1A4K3 Cow SwissProt: Q16531 Human SwissProt: Q3U1J4 Mouse SwissProt: Q9ESW0 Rat Unigene: 290758 Human Unigene: 289915 Mouse Unigene: 466856 Mouse Unigene: 8402 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DNA损伤结合蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid