颗粒溶素抗体
规格：1mg/1ml
英文名： GNLY
别名： Granulysin; D2S69E; LAG2; 519; LAG 2; Lymphocyte activation gene 2; Lymphokine LAG 2; NKG 5; NKG5; Protein NKG5; T cell activation protein 519; T lymphocyte activation gene 519; TLA519.
分子量： 14kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GNLY/NKG
交叉反应：Human,
细胞定位：分泌型蛋白
颗粒溶素抗体产品介绍：background: The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]. Function: Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis. 颗粒溶素抗体Subcellular Location: Secreted. Note=Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation. Tissue Specificity: Expressed in natural killer and T-cells. Post-translational modifications: A 9 kDa form is produced by proteolytic processing of a 15 kDa protein. Similarity: Contains 1 saposin B-type domain. Gene ID: 10578 Database links: Entrez Gene: 10578 Human Omim: 188855 Human颗粒溶素抗体 SwissProt: P22749 Human Unigene: 105806 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. granulysin是近年来新发现的一种细胞毒性效应蛋白,是由激活的细胞毒性T**细胞(cytotoxic T lymphocytes, CTL)和自然杀伤细胞(natural killer, NK)产生的一种阳离子蛋白质.能够杀伤微生物和肿瘤细胞.
颗粒溶素抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid