**细胞抗原75抗体
规格：1mg/1ml
英文名： Ly75/CD205
别名： C-type lectin domain family 13 member B; CD 205; CD205; CD205 antigen; CLEC 13B; CLEC13B; DEC 205; DEC-205; DEC205; gp200; gp200 MR6; gp200-MR6; LY 75; Ly-75; LY75; LY75_HUMAN; Lymphocyte antigen 75;
分子量： 195kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DEC-205
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig,
细胞定位：细胞膜
**细胞抗原75抗体产品介绍：background: Ly75 is expressed in spleen, thymus, colon and peripheral blood lymphocytes and causes reduced proliferation of B-lymphocytes as well as acting as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Ly75 is also detected in myeloid and B lymphoid cell lines and isoforms 2 and 3 are expressed in Hodgkin and Reed-Sternberg (HRS) cells (malignant Hodgkin lymphoma cells). Function: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B-lymphocytes. **细胞抗原75抗体Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. Post-translational modifications: N-glycosylated. Similarity: Contains 10 C-type lectin domains. **细胞抗原75抗体Contains 1 fibronectin type-II domain. Contains 1 ricin B-type lectin domain. Gene ID: 4065 Database links: Entrez Gene: 100526664 Human Entrez Gene: 4065 Human Entrez Gene: 17076 Mouse Omim: 604524 Human SwissProt: O60449 Human SwissProt: Q60767 Mouse Unigene: 153563 Human Unigene: 2074 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
**细胞抗原75抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞类型标志物 b-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid