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NK细胞受体BY55抗体

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产品名称: NK细胞受体BY55抗体
产品型号: CD160
产品展商: 单克隆抗体/多克隆抗体
产品文档: 无相关文档

简单介绍

NK细胞受体BY55抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。NK细胞受体BY55抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。


NK细胞受体BY55抗体  的详细介绍

NK细胞受体BY55抗体

规格:1mg/1ml

英文名: CD160

别名: By55; Natural killer cell receptor BY55; BY55; CD160 antigen [Precursor]; CD160 molecule; FLJ46513; Natural killer cell receptor BY55; NK1; NK28; BY55_HUMAN.

分子量: 14.7kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:Polyclonal

亚型:IgG

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human CD160

交叉反应:Human, Mouse, Rat, Dog,

细胞定位:细胞膜

NK细胞受体BY55抗体产品介绍:background: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to NK细胞受体BY55抗体TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008] Function: Receptor showing broad specificity for both classical and non-classical MHC class I molecules. Subunit: Homomultimer; disulfide-linked. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Tissue Specificity: Expressed in spleen, peripheral blood, and small intestine. Expression NK细胞受体BY55抗体is restricted to functional NK and T cytotoxic lymphocytes. Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. Gene ID: 11126 Database links: Entrez Gene: 11126 Human Omim: 604463 Human SwissProt: O95971 Human Unigene: 488237 Human Unigene: 740780 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

NK细胞受体BY55抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:细胞生物  **学  细胞膜受体  自然杀伤细胞  t-**细胞  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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