CD99抗体
规格：1mg/1ml
英文名： CD99
别名： T-cell surface glycoprotein E; T cell surface glycoprotein E2 precursor; 12E7; Antigen identified by monoclonal 12E7 Y homolog; Antigen identified by monoclonal antibodies 12E7 F21 and O13; CD 99; CD9
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse CD99
交叉反应：Mouse, Rat,
细胞定位：细胞膜
CD99抗体产品介绍：background: The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, CD99抗体Jul 2008]. Function: Involved in T-cell adhesion processes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Subunit: Homodimer. Interacts with PILRB. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Natural killer cells. Similarity: Belongs to the CD99 family.CD99抗体 Gene ID: 673094 Database links: Entrez Gene: 4267 Human Entrez Gene: 673094 Mouse Omim: 313470 Human SwissProt: P14209 Human SwissProt: Q8VCN6 Mouse Unigene: 653349 Human Unigene: 423040 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CD99（P30/32MIC2）是一种跨膜蛋白，为MIC2基因产物。分布于**细胞、胸腺皮质细胞、卵巢的颗粒细胞、胰岛细胞和睾丸支持细胞。
CD99抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞表面分子 糖蛋白 细胞类型标志物 t-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid