CD83抗体
规格：1mg/1ml
英文名： CD83
别名： B cell activation 45kDa cell surface glycoprotein Ig superfamily; B cell activation protein; BL11; BL11 PEN; CD83 molecule; Cell surface protein HB15; HB15; MGC130312; MGC130313; Cell surface protein
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD83
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
CD83抗体产品介绍：background: The CD83 antigen is a 186 amino acid single chain glycoprotein. This molecule is a member of the immunoglobulin superfamily and is composed of an extracellular V type immunoglobulin-like single domain, a transmembrane region, and a short, 40 amino acid cytoplasmic tail. CD83 antigen undergoes extensive post translational glycosylation, as the determined Mr is twice the predicted size of the core protein. However, CD83+ cells have a unique cell surface immunophenotype that does not correlate with that of T cells, B cells, NK cells, or cells of the myelomonocytic lineage. CD83+ cells coexpress the highest levels of MHC class II molecules, when compared with other leucocyte lineages. They also coexpress T cell markers (CD2, CD5), B cell markers (CD40, CD78), myeloid cell markers (CD13,CD83抗体 CD33, CD36) and cytokine receptors, as well as other cell surface molecules. Function: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation (By similarity). Subunit: Monomer. Subcellular Location: Membrane; Single-pass type I CD83抗体membrane protein. Tissue Specificity: Abundantly expressed in spleen and brain, but is also detected in most tissues analyzed. Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. Gene ID: 9308 Database links: Entrez Gene: 9308 Human Entrez Gene: 12522 Mouse Entrez Gene: 361226 Rat Omim: 604534 Human SwissProt: Q01151 Human SwissProt: O88324 Mouse Unigene: 595133 Human Unigene: 57175 Mouse Unigene: 20096 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD83抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 细胞膜受体 t-**细胞 b-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid