G2期/S期应答相关蛋白1抗体
规格:1mg/1ml
英文名: GTSE-1
别名: G2 and S phase-expressed protein 1; B99; B99 homolog; G 2 and S phase expressed 1; G two S phase expressed protein 1; GTSE 1; GTSE-1; GTSE1; GTSE1_HUMAN.
分子量: 77kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GTSE-1
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow,
细胞定位:细胞核
G2期/S期应答相关蛋白1抗体产品介绍:background: The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce G2期/S期应答相关蛋白1抗体apoptosis. [provided by RefSeq, Jul 2008] Function: May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression. Subcellular Location: Cytoplasm, cytoskeleton. Note=Associated with microtubules. Post-translational modifications: Phosphorylated in mitosis. Similarity:G2期/S期应答相关蛋白1抗体 Sequence=CAQ09324.2; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAQ10552.2; Type=Erroneous initiation; Note=Translation N-terminally shortened. Gene ID: 51512 Database links: Entrez Gene: 51512 Human Omim: 607477 Human SwissProt: Q9NYZ3 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G2期/S期应答相关蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 细胞周期蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid