锌指蛋白217抗体
规格：1mg/1ml
英文名： ZNF217
别名： zinc finger protein 217; ZABC 1; ZABC1; ZN 217; ZN217; ZNF 217; 4933431C08Rik; AW987152; Gm562; Zfp217; ZN217_HUMAN .
分子量： 115kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZNF217
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：
锌指蛋白217抗体产品介绍：background: ZNF217 (Zinc-finger protein 217) is a Kruppel-like zinc-finger protein which functions as a transcriptional repressor protein and forms a complex with a number of proteins including CoREST, BHC110/LSD1, HDAC2 and CtBP1. ZNF217 has been shown to repress E-cadherin promoter activity. ZNF217 is overexpressed in a number of cancers including breast and ovarian. ZNF217 and its associated proteins have been implicated in a novel pathway that is involved in cancer progression. Function: Binds to the promoters of target genes and functions as epressor. Promotes cell proliferation and antagonizes cell death. romotes phosphorylation of AKT1 at 'Ser-473'. Subunit: Component of a histone deacetylase complex that contains DAC2, KDM1A, CTBP1 and ZNF217. May be a component of 锌指蛋白217抗体a BHC histone eacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, DM1A, RCOR1/CoREST, PHF21A/BHC80, ZMYM2, ZNF217, ZMYM3, GSE1 and TF2I. Interacts with CTBP1 and CTBP2. Subcellular Location: Nucleus (Probable). Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 7 C2H2-type zinc fingers. Gene ID: 7764 Database links: Entrez Gene: 7764 Human Omim: 602967 锌指蛋白217抗体Human SwissProt: O75362 Human Unigene: 155040 Human Unigene: 711564 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白217抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 染色质和核信号 信号转导 转录调节因子 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid