水通道蛋白-7抗体
规格：1mg/1ml
英文名： AQP7
别名： aquaporin Protein-7; AQP7; AQP7L; AQP9; AQPap; Aqpap7; Aquaporin 7;Aquaporin-7 like; MGC149555; MGC149556; AQP7_HUMAN.
分子量： 37kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AQP7
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
细胞定位：细胞膜
水通道蛋白-7抗体产品介绍：background: Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein "aquaporin". Over the last decade, genes for several members of aquaporin family have been cloned, expressed, and their distribution studied in many tissues. AQP0 or MIP26 (major intrinsic protein 26kD), and Aquaporin 1 (AQP1, purified from red cells) also called CHIP28 (channel forming integral protein, 28kD; 268aa; gene locus 7p14) has been the foundation of the growing family of aquaporin. The lens specific AQP0 r水通道蛋白-7抗体epresents up to 80% of total lens membrane protein. Defects in MIP26 are cause of autosomal dominant cataract. The cataract Fraser mutation (CATFR or Shriveled) is a transposon induced splicing error that substitutes a long terminal repeat sequence for the C terminus of MIP. The lens opacity mutation (LOP) is an amino acid substitution that inhibits targeting of MIP to the cell membrane. Function: Forms a channel for water and glycerol (By similarity). Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the MIP/aquaporin 水通道蛋白-7抗体(TC 1.A.8) family. Gene ID: 364 Database links: Entrez Gene: 364 Human Entrez Gene: 11832 Mouse Entrez Gene: 29171 Rat Omim: 602974 Human SwissProt: O14520 Human SwissProt: O54794 Mouse SwissProt: P56403 Rat Unigene: 455323 Human Unigene: 8728 Mouse Unigene: 11111 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
水通道蛋白-7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid