翻译延伸因子EF-1a抗体
规格：1mg/1ml
英文名： eEF1A1
别名： Elongation Factor 1, Alpha; EF1 Alpha; eukaryotic translation elongation factor 1 alpha 1; CCS3; eEF1A-1; EF-Tu; EF1A; Elongation factor Tu; GRAF-1EF; PTI1; elongation factor 1-alpha 1; EEF-1; EEF1A;
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EF1 alph
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞浆
翻译延伸因子EF-1a抗体产品介绍：background: eEF1A1 is an isoform of the alpha subunit of the elongation factor 1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. It promotes the GTP dependent binding of aminoacyl tRNA to the A site of ribosomes during protein biosynthesis. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome (referenced from entrez gene and swissprot). Function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Subcellular Location: Cytoplasm. Tissue Specificity: Brain, placenta, lung, liver, kidney, pancreas 翻译延伸因子EF-1a抗体but barely detectable in heart and skeletal muscle Post-translational modifications: ISGylated. Similarity: Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. Gene ID: 1915 Database links: Entrez Gene: 1915 Human Entrez Gene: 13627 Mouse Entrez Gene: 171361 Rat Omim: 130590 Human SwissProt: P68104 Human SwissProt: P10126 Mouse SwissProt: P62630 Rat Unigene: 520703翻译延伸因子EF-1a抗体 Human Unigene: 535192 Human Unigene: 586423 Human Unigene: 695681 Human Unigene: 713109 Human Unigene: 138471 Mouse Unigene: 335315 Mouse Unigene: 360075 Mouse Unigene: 391071 Mouse Unigene: 468942 Mouse Unigene: 144660 Rat Unigene: 965 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 肽链延长因子1A-1(peptide elongation factor 1A-1,eEF1A-1)是真核细胞蛋白翻译过程中肽链延长复合物的重要构成成分,具有调节蛋白合成及促发凋亡等多种作用.
翻译延伸因子EF-1a抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 细胞凋亡 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid