CD30抗体
规格：1mg/1ml
英文名： CD30
别名： CD 30; CD30; CD30 antigen; CD30L receptor; Cytokine receptor CD30; D1S166E; KI 1; Ki 1 antigen; Ki-1 antigen; KI1; Lymphocyte activation antigen CD30; TNFRSF 8; TNFRSF8; TNFRSF8; TNR8_HUMAN; Tumor Nec
分子量： 62kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD30
交叉反应：Human, Rabbit,
细胞定位：细胞浆 细胞膜
CD30抗体产品介绍：background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] Function: Receptor for TNFSF8/CD30L. May play a roleCD30抗体 in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. Subunit: Interacts with TRAF1, TRAF2, TRAF3 and TRAF5. Subcellular Location: Isoform Long: Cell membrane; CD30抗体Single-pass type I membrane protein. Isoform Short: Cytoplasm. Post-translational modifications: Phosphorylated on serine and tyrosine residues. Similarity: Contains 6 TNFR-Cys repeats. Gene ID: 943 Database links: Entrez Gene: 943 Human Omim: 153243 Human SwissProt: P28908 Human Unigene: 1314 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CD30是一种单链糖蛋白，标记活化T和B**细胞，R-S细胞和部分**滤泡间区**母细胞。CD30是霍奇金**瘤的一个特异性标记，也是大细胞间变型**瘤的诊断型标志。
CD30抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 细胞类型标志物 肿瘤细胞生物标志物 细胞因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid