CD27抗体
规格：1mg/1ml
英文名： CD27
别名： CD 27; Cd27; CD27 antigen; CD27 molecule; CD27_HUMAN; CD27L receptor; LPFS2; MGC20393; OTTHUMP00000238557; S152; T cell activation antigen CD27; T cell antivation antigen S152; T-cell activation antig
分子量： 27kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD27
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：细胞膜
CD27抗体产品介绍：background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] Function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. CD27抗体Subunit: Homodimer. Interacts with SIVA1 and TRAF2. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Found in most T-lymphocytes. Post-translational modifications: Phosphorylated. O-glycosylated with core 1 or possibly core 8 glycans. Similarity: Contains 3 TNFR-Cys repeats. Gene ID: 939 Database links: Entrez Gene: 939 Human Entrez Gene: 21940 Mouse Entrez Gene:CD27抗体 500318 Rat Omim: 186711 Human SwissProt: P26842 Human SwissProt: P41272 Mouse Unigene: 355307 Human Unigene: 367714 Mouse Unigene: 134200 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD27抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 干细胞 细胞类型标志物 **细胞 t-**细胞 细胞因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid