巨噬细胞炎性蛋白16抗体
规格：1mg/1ml
英文名： CCL16/LEC
别名： C-C motif chemokine 16; CCL16; CCL16_HUMAN; Chemokine (C-C motif) ligand 16; Chemokine CC-4; Chemokine LEC; CKb12; CKb12; HCC-4; HCC4; HCC4; IL-10-inducible chemokine; IL10 inducible chemokine; IL10 i
分子量： 11kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCL16 C-
交叉反应：Human,
细胞定位：分泌型蛋白
巨噬细胞炎性蛋白16抗体产品介绍：background: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008] Function: Shows chemotactic activity for lymphocytes and 巨噬细胞炎性蛋白16抗体monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. Subcellular Location: Secreted. Tissue Specificity: Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including 巨噬细胞炎性蛋白16抗体natural killer cells, gamma-delta T-cells, and some T-cell clones. Similarity: Belongs to the intercrine beta (chemokine CC) family. Gene ID: 6360 Database links: Entrez Gene: 6360 Human Omim: 601394 Human SwissProt: O15467 Human SwissProt: Q4KKU0 Human Unigene: 10458 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
巨噬细胞炎性蛋白16抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid