白细胞介素-13受体a1抗体
规格：1mg/1ml
英文名： IL-13Ra1
别名： Interleukin-13 receptor subunit alpha-1; CD213A1; CD213A1 Antigen; IL 13R alpha 1; IL 13Ra; IL13 receptor alpha 1; IL13R; IL13RA; IL13RA1; Interleukin 13 receptor alpha 1 chain; NR4; I13R1_HUMAN.
分子量： 47kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IL-13Ra1
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
白细胞介素-13受体a1抗体产品介绍：background: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. Function: Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory 白细胞介素-13受体a1抗体protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. Subunit: Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. Interacts with TRAF3IP1. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Spleen, liver, thymus, heart, lung, kidney, testis, stomach, brain, skin, and colon; but not skeletal muscle. Similarity: Belongs to the type I cytokine receptor family. Type 5 subfamily.白细胞介素-13受体a1抗体Gene ID: 3597 Database links: Entrez Gene: 3597 Human Entrez Gene: 16164 Mouse Omim: 300119 Human SwissProt: P78552 Human SwissProt: O09030 Mouse Unigene: 496646 Human Unigene: 24208 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
白细胞介素-13受体a1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid