自噬相关蛋白7抗体
规格：1mg/1ml
英文名： APG7
别名： Apg 7; ATG7; APG7 autophagy 7 like; APG7 autophagy 7-like (S. cerevisiae); APG7 like; APG7, S. cerevisiae, homolog of; APG7L; ATG 7; atg7; ATG7 autophagy related 7 homolog (S. cerevisiae); ATG7 autoph
分子量： 78kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ATG7
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
细胞定位：细胞浆
自噬相关蛋白7抗体产品介绍：background: This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. [provided by RefSeq, Jan 2009]. Function: Functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. Forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. Also acts as an E1 enzyme for ATG12 自噬相关蛋白7抗体conjugation to ATG5 and ATG3. Subunit: Homodimer. Interacts with ATG3 and ATG12. The complex, composed of ATG3 and ATG7, plays a role in the conjugation of ATG12 to ATG5. Subcellular Location: Cytoplasm (Probable). Tissue Specificity: Widely expressed, 自噬相关蛋白7抗体especially in kidney, liver, lymph nodes and bone marrow. Similarity: Belongs to the ATG7 family. Gene ID: 10533 Database links: Entrez Gene: 10533 Human Entrez Gene: 415961 Chicken Entrez Gene: 74244 Mouse Entrez Gene: 312647 Rat Omim: 608760 Human SwissProt: Q5ZKY2 Chicken SwissProt: O95352 Human SwissProt: Q9D906 Mouse SwissProt: Q641Y5 Rat Unigene: 38032 Human Unigene: 275332 Mouse Unigene: 162765 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
自噬相关蛋白7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-100 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 细胞凋亡 细胞自噬
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid