粘蛋白-5B抗体
规格：1mg/1ml
英文名： MUC5B
别名： High molecular weight salivary mucin MG1; MUC5; Mucin 5 subtype B, tracheobronchial; Mucin 5B; Sublingual gland mucin; 2300002I04Rik; A130042M24; AV085033; Cervical mucin; Cervical mucin MUC5B; High m
分子量： 590kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human mucin 5B
交叉反应：Human, Mouse, Rat,
细胞定位：分泌型蛋白
粘蛋白-5B抗体产品介绍：background: Tumor Markers Mucins are high molecular mass, highly glycosylated macromolecules that are the major components of mucus secretions. MUC5B is a salivary mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva. It is composed of 14.9% protein, 78.1% carbohydrate, and 7% sulfate (Troxler et al., 1995 [PubMed 8554565]).[supplied by OMIM] Function: Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. Subcellular Location: Secreted. Tissue Specificity: Expressed on surface airway epithelia. Expressed mainly in mucous cells of submucosal glands of airway tissues. Highly expressed in the sublingual gland. Also found in submaxillary glands, endocervix, gall bladder, and pancreas.粘蛋白-5B抗体 Post-translational modifications: Highly glycosylated. C-, N- and O-glycosylated. C-mannosylated in the Cys-rich subdomains probably on the first Trp residue of the WXXW motif. Highly O-glycosylated in the Ser/Thr-rich tandem repeat (TR) region. The repeat region is about 59% O-glycosylated with a high abundance of NeuAc(2)Hex(1)HexNac1-ol. Similarity: Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 3 HAT repeats. Contains 3 TIL (trypsin inhibitory-like) domains. Contains 3 VWFC domains. Contains 4 VWFD domains. Gene ID: 4703粘蛋白-5B抗体 Database links: Entrez Gene: 374027 Chicken Entrez Gene: 4703 Human Entrez Gene: 17996 Mouse Entrez Gene: 311029 Rat Omim: 161650 Human SwissProt: P20929 Human Unigene: 588655 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
粘蛋白-5B抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid