N-甲基嘌呤DNA糖基化酶
规格：1mg/1ml
英文名： APNG/MPG
别名： MPG; N-methylpurine-DNA glycosylase isoform a; DNA 3 methyladenine glycosylase; 3 alkyladenine DNA glycosylase; AAG; ADPG; Alkyladenine DNA glycosylase; anpg ; APNG; MDG; N methylpurine DNA glycosiras
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human APNG/MPG
交叉反应：Human, Mouse, Rat, Pig, Cow,
细胞定位：细胞核
N-甲基嘌呤DNA糖基化酶产品介绍：background: MPG (N-methylpurine DNA glycosylase, or 3-methyladenine (3MeA) DNA glycosylase) repairs the 3MeA lethal lesion blocking DNA replication in Escherichia coli. Analysis of human cDNA libraries found a cDNA that would hybridize to human genomic DNA but not to E. coli or yeast DNA. This MPG gene has been mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines. Function: Hydrolysis of the deoxyribose N-glycosidic bond to N-甲基嘌呤DNA糖基化酶excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. Subunit: Belongs to the DNA glycosylase MPG family. Subcellular Location: Nucleus. Similarity: Belongs to the DNA glycosylase MPG family. Gene ID: 4350 Database links: Entrez Gene: 4350 Human Entrez Gene: 268395 Mouse Entrez Gene: 24561 Rat Omim: 156565 Human SwissProt: P29372 Human SwissProt: N-甲基嘌呤DNA糖基化酶Q04841 Mouse SwissProt: P23571 Rat Unigene: 459596 Human Unigene: 263161 Mouse Unigene: 482070 Mouse Unigene: 11241 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
N-甲基嘌呤DNA糖基化酶产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 染色质和核信号 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid