NK细胞受体2A抗体
规格:1mg/1ml
英文名: NKG2A
别名: KLRC1; C lectin type II protein; CD159 antigen like family member A; CD159A; Killer cell lectin like receptor subfamily C member 1; MGC13374; MGC59791; Natural killer cell lectin; Natural killer group
分子量: 28kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from mouse NKG2A
交叉反应:Mouse, Rat,
细胞定位:
NK细胞受体2A抗体产品介绍:background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript NK细胞受体2A抗体variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008] Function: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Subunit: Can form disulfide-bonded heterodimer with CD94. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Natural killer cells. Similarity: Contains 1 C-type lectin NK细胞受体2A抗体domain. Gene ID: 3821 Database links: Entrez Gene: 3821 Human Entrez Gene: 16641 Mouse Omim: 161555 Human SwissProt: P26715 Human Unigene: 512576 Human Unigene: 56899 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 自然杀伤细胞活化性受体2A
NK细胞受体2A抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid