神经元突触前膜蛋白抗体
规格：1mg/1ml
英文名： Amphiphysin
别名： Amphiphysin; Amp; AMPH 1; AMPH1; Amphiphysin (Stiff-Man syndrome with breast cancer 128kD autoantigen); Amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen); Amphiphysin I; CG8604; D
分子量： 76kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Amphiphy
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
神经元突触前膜蛋白抗体产品介绍：background: Amphiphysin is associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants (Amphiphysin 1 and Amphiphysin 2) encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. Function: May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton. Subunit: Heterodimer with BIN1神经元突触前膜蛋白抗体. Binds SH3GLB1 and AP2A2. Interacts with AP2B1. Subcellular Location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Tissue Specificity: Neurons, certain endocrine cell types and spermatocytes. Similarity: Contains 1 BAR domain. Contains 1 SH3 domain. Gene ID: 273 Database links: Entrez Gene: 273 Human Entrez Gene: 218038 Mouse Entrez Gene: 60668 Rat Omim: 600418 Human SwissProt: P49418 Human SwissProt: Q7TQF7 Mouse SwissProt: O08838 Rat Unigene: 神经元突触前膜蛋白抗体592182 Human Unigene: 101650 Mouse Unigene: 44463 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经元突触前膜蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid