α-中连蛋白抗体
规格：1mg/1ml
英文名： alpha Internexin
别名： a-Internexin; Alpha-Internexin; Alpha-Internexin; 66 kDa neurofilament protein; Alpha Inx; INA; Internexin neuronal intermediate filament protein alpha; MGC12702; NEF 5; NEF5; Neurofilament 5 (66kD);
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NF-66
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
α-中连蛋白抗体细胞定位：细胞浆
产品介绍：background: eurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. [provided by RefSeq, Jun 2009] Function: Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to α-中连蛋白抗体form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges. Subcellular Location: Cytoplasmic. Tissue Specificity: Found predominantly in ***** CNS. Post-translational modifications: O-glycosylated (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the intermediate filament family. Gene ID: 9118 Database links: Entrez Gene: 9118 Human Entrez Gene: 226180 Mouse Entrez Gene: 24503 Rat Omim: 605338 Human SwissProt: Q16352 Human SwissProt: P46660 Mouse SwissProt: P23565 α-中连蛋白抗体Rat Unigene: 500916 Human Unigene: 276251 Mouse Unigene: 88941 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
α-中连蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 干细胞 细胞粘附分子 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid