醛缩酶A抗体
规格：1mg/1ml
英文名： Aldolase A
别名： ALDA; Aldo1; ALDOA; ALDOA_HUMAN; Aldolase 1; Aldolase A; Aldolase A fructose bisphosphatase; Aldolase A fructose bisphosphate; FRUCTOALDOLASE A; Fructose 1 6 bisphosphate triosephosphate lyase; Fructo
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Aldolase
交叉反应：Human, Mouse, Rat, Horse, Rabbit,
细胞定位：
醛缩酶A抗体产品介绍：background: Research areas:Cancer //Cancer Metabolism //Metabolic signaling pathway < Aldolase A (fructose bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3 phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in ***** muscle. Aldolase A expression is repressed in ***** liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode 醛缩酶A抗体the same protein. Cellular localization:Cytoplasmic Tissue Specificity:***** liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Function: Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein. Subunit: Homotetramer. Interacts with SNX9 and WAS. DISEASE: Glycogen storage disease 12 (GSD12) [MIM:611881]: A metabolic disorder associated醛缩酶A抗体 with increased hepatic glycogen and hemolytic anemia. It may lead to myopathy with exercise intolerance and rhabdomyolysis. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the class I fructose-bisphosphate aldolase family. Gene ID: 226 Database links: Entrez Gene: 226 Human Omim: 103850 Human SwissProt: P04075 Human Unigene: 513490 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
醛缩酶A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-300 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid