甘氨酸-N-甲基转移酶
规格：1mg/1ml
英文名： GNMT
别名： Glycine N methyltransferase; Recombinant Human Glycine N-Methyltransferase.
分子量： 32kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GNMT
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞浆
甘氨酸-N-甲基转移酶产品介绍：background: GNMT catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). It plays a possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine. Function: Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine. Subunit: Homotetramer. Subcellular 甘氨酸-N-甲基转移酶Location: Cytoplasm. Tissue Specificity: Abundant in liver. DISEASE: Defects in GNMT are the cause of glycine N-methyltransferase deficiency (GNMT deficiency) [MIM:606664]; also known as hypermethioninemia. The only clinical abnormalities in patients with this 甘氨酸-N-甲基转移酶deficiency are mild hepatomegaly and chronic elevation of serum transaminases. Similarity: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甘氨酸-N-甲基转移酶产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid