信号识别颗粒抗体
规格：1mg/1ml
英文名： Signal recognition particle
别名： Signal recognition particle 68 kDa; Signal recognition particle subunit SRP68; Signal recognition particle 68 kDa protein; SRP 68; SRP68; Srp68; SRP68_HUMAN.
分子量： 71kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Signal r
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位：
信号识别颗粒抗体产品介绍：background: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. Function: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and 信号识别颗粒抗体possibly participate in the elongation arrest function. Subunit: Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. Subcellular Location: Cytoplasm. Nucleus, nucleolus. Similarity: Belongs to the SRP68 family. Database links: UniProtKB/Swiss-Prot: Q9UHB9.2 Important Note: This product as supplied is intended信号识别颗粒抗体 for research use only, not for use in human, therapeutic or diagnostic applications. 信号识别颗粒(Signalrecognitionparticle,SRP)是介导蛋白识别转运其中普遍存在的机制之一,细胞内蛋白质的定向转移是蛋白质质量数量控制体系的一个重要环节,SRP对参与这一过程的功能基因和蛋白,尤其是蛋白的靶向输送机制的研究对揭示细胞的分化、代谢和病变具有重大的理论意义.
产信号识别颗粒抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 染色质和核信号 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid