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RNA聚合酶I抗体

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产品名称: RNA聚合酶I抗体
产品型号: UBF1
产品展商: 单克隆抗体/多克隆抗体
产品文档: 无相关文档

简单介绍

RNA聚合酶I抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。RNA聚合酶I抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。


RNA聚合酶I抗体  的详细介绍

RNA聚合酶I抗体

规格:1mg/1ml

英文名: UBF1

别名: UBF; NOR 90; Nucleolar transcription factor 1; UBF 1; UBF-1; UBF; UBTF; Autoantigen NOR-90; Upstream-binding factor 1; Upstream binding factor 1; upstream binding transcription factor, RNA polymerase

分子量: 89kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:Polyclonal

亚型:IgG

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human UBF1

交叉反应:Human, Mouse, Rat, Cow,

细胞定位:细胞核

RNA聚合酶I抗体产品介绍:background: This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.RNA聚合酶I抗体 [provided by RefSeq, Aug 2011] Function: Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. Subcellular Location: Nucleus Post-translational modifications: Phosphorylated and activated by PIK3CA. Similarity: Contains 6 HMG box RNA聚合酶I抗体DNA-binding domains. Gene ID: 7343 Database links: Entrez Gene: 7343 Human Entrez Gene: 21429 Mouse Entrez Gene: 25574 Rat Omim: 600673 Human SwissProt: P17480 Human SwissProt: P25976 Mouse SwissProt: P25977 Rat Unigene: 89781 Human Unigene: 2845 Mouse Unigene: 22469 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

RNA聚合酶I抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:肿瘤  细胞生物  **学  染色质和核信号  转录调节因子  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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