骨形态发生蛋白7抗体
规格：1mg/1ml
英文名： BMP7
别名： bone morphogenetic protein 7 precursor; osteogenic protein 1; BMP-7; OP-1; BMP 7; Bone morphogenic protein 7; Eptotermin alfa; OP 1; OP1; BMP7_HUMAN.
分子量： 15.7/47kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BMP7
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：分泌型蛋白
骨形态发生蛋白7抗体产品介绍：background: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq]. Function: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Subunit: Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with 骨形态发生蛋白7抗体TWSG1. Subcellular Location: Secreted. Tissue Specificity: Expressed in the kidney and bladder. Lower levels seen in the brain. Post-translational modifications: Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014). Similarity: Belongs to the TGF-beta family. Gene ID: 655 Database links: Entrez Gene: 骨形态发生蛋白7抗体477270 Dog Entrez Gene: 655 Human Entrez Gene: 12162 Mouse Entrez Gene: 492315 Pig Entrez Gene: 85272 Rat Omim: 112267 Human SwissProt: P18075 Human SwissProt: P23359 Mouse Unigene: 473163 Human Unigene: 595 Mouse Unigene: 18030 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 骨形态发生蛋白7（BMP-7）是转化生长因子β超家族成员,参与器官发生,细胞增殖、分化及凋亡等.
产骨形态发生蛋白7抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞凋亡 生长因子和** 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid