缺氧诱导蛋白HIG1抗体
规格：1mg/1ml
英文名： TDRD9
别名： C14orf75; chromosome 14 open reading frame 75; HIG 1; HIG1; Hypoxia inducible HIG 1; MGC135025; Putative ATP dependent RNA helicase TDRD9; Putative ATP-dependent RNA helicase TDRD9; TDRD 9; Tdrd9; TDR
分子量： 155kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TDRD9/HI
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位：细胞核 细胞浆
缺氧诱导蛋白HIG1抗体产品介绍：background: Probable ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with PIWIL4 and the piP-bodies suggests a participation in the secondary piRNAs metabolic process. Function: Probable ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process,缺氧诱导蛋白HIG1抗体 which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with PIWIL4 and the piP-bodies suggests a participation in the secondary piRNAs metabolic process Subunit: Interacts with piRNA-associated proteins PIWIL1 and PIWIL4 Subcellular Location: Cytoplasm. Nucleus. Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis. Specifically localizes to piP-bodies, a subset of the nuage which contains secondary piRNAs. PIWIL2 is required for its localization to piP-bodies. Similarity: Belongs to 缺氧诱导蛋白HIG1抗体the DEAD box helicase family. DEAH subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Contains 1 Tudor domain. Gene ID: 122402 Database links: Entrez Gene: 122402 Human Entrez Gene: 74691 Mouse Entrez Gene: 299343 Rat SwissProt: Q8NDG6 Human SwissProt: Q14BI7 Mouse SwissProt: Q3MHU3 Rat Unigene: 21454 Human Unigene: 60648 Mouse Unigene: 126122 Rat Unigene: 224769 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
缺氧诱导蛋白HIG1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid