RNA结合蛋白19抗体
规格：1mg/1ml
英文名： RBM19
别名： 1200009A02Rik; AV302714; NPO; Probable RNA-binding protein 19; RBM19; RBM19_HUMAN; RNA-binding motif protein 19.
分子量： 108kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RBM19
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
RNA结合蛋白19抗体产品介绍：Function: Plays a role in embryo pre-implantation development. Subcellular Location: Nucleus > nucleolus. Nucleus > nucleoplasm. Cytoplasm. Chromosome. In discrete foci distributed throughout the cytoplasm and nucleoplasm during the 4 to 8 cell stages and the morula stage, but not in the periphery of the nucleolar precursor body (NPB). During blastocyst development, becomes increasingly localized to the nucleolus and less to the cytoplasm. At the late blastocyst stage, localized predominantly in the nucleolus. Localized in the nucleolus during interphase and to the perichromosomal sheath during mitosis. Does not colocalize in the cytoplasm with GW182 in P-bodies. RNA结合蛋白19抗体May translocate to the nucleolus upon early embryonic development (By similarity). Colocalizes with NPM1 during interphase. By late prophase, metaphase, anaphase and telophase, associates with the chromosome periphery. By telophase localizes to NPB. Tissue Specificity: Expressed in the crypts of Lieberkuhn of the intestine and in intestinal neoplasia (at protein level). Similarity: Belongs to the RRM MRD1 family. Contains 6 RRM (RNA recognition motif) domains. Database links: Entrez Gene: 9904 Human Entrez Gene: 74111 Mouse Entrez Gene:RNA结合蛋白19抗体 304512 Rat SwissProt: Q9Y4C8 Human SwissProt: Q8R3C6 Mouse Unigene: 7482 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RNA结合蛋白19抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 转录调节因子 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid