溶质载体转运蛋白家族39成员A13抗体
规格：1mg/1ml
英文名： SLC39A13
别名： FLJ25785; LIV-1 subfamily of ZIP zinc transporter 9; LZT-Hs9; S39AD_HUMAN; SLC39A13; solute carrier family 39 (metal ion transporter), member 13; solute carrier family 39 (zinc transporter), member 13
分子量： 39kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC39A13
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea Pig,
细胞定位：细胞膜
溶质载体转运蛋白家族39成员A13抗体产品介绍：background: This gene encodes a member of the LIV-1 subfamily of the ZIP transporter family. The encoded transmembrane protein functions as a zinc transporter. Mutations in this gene have been associated with the spondylocheiro dysplastic form of Ehlers-Danlos syndrome.[provided by RefSeq, Mar 2010] Function: Acts as a zinc-influx transporter. Subcellular Location: Membrane. DISEASE: Defects in SLC39A13 are the cause of Ehlers-Danlos syndrome-like spondylocheirodysplasia (SCD-EDS) [MIM:612350]. SCD-EDS is a 'spondylocheiro dysplastic form of Ehlers-Danlos syndrome'. The syndrome consists of a generalized skeletal dysplasia involving mainly the spine (spondylo) and striking clinical abnormalities of the hands (cheiro) in addition to the EDS-like features. Clinical features included postnatal growth retardation, moderate short stature, protuberant eyes with bluish sclerae, hands with finely wrinkled palms, atrophy of the thenar muscles, 溶质载体转运蛋白家族39成员A13抗体and tapering fingers. Patients have thin, hyperelastic skin and hypermobile small joints consistent with an Ehlers-Danlos-like phenotype. Radiologic features included mild to moderate platyspondyly, mild to moderate osteopenia of the spine, small ileum, flat proximal femoral epiphyses, short, wide femoral necks, and broad metaphyses (elbows, knees, wrists, and interphalangeal joints). Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. Database links: Entrez Gene: 101095193 Cat Entrez Gene: 743682 Chimpanzee Entrez Gene: 614946 溶质载体转运蛋白家族39成员A13抗体Cow Entrez Gene: 475981 Dog Entrez Gene: 91252 Human Entrez Gene: 68427 Mouse Entrez Gene: 713420 Rhesus monkey Omim: 608735 Human SwissProt: A5D7H1 Cow SwissProt: Q96H72 Human SwissProt: Q8BZH0 Mouse Unigene: 523664 Human Unigene: 192375 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet 溶质载体转运蛋白家族39成员A13抗体tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转运蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid