溶质载体家族25成员24抗体
规格:1mg/1ml
英文名: SLC25A24
别名: APC 1; APC1; Calcium binding mitochondrial carrier protein SCaMC 1; Calcium binding transporter; DKFZp586G0123; MCSC 1; MCSC1; Mitochondrial ATP Mg/Pi carrier protein 1; Mitochondrial ATP Mg/Pi transp
分子量: 51kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLC25A24
交叉反应:Human, Mouse, Cow, Rabbit,
细胞定位:
溶质载体家族25成员24抗体产品介绍:background: SLC25A24 (Solute carrier family 25 member 24) is a calcium-dependent mitochondrial solute carrier. It may act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria. Function: Calcium-dependent mitochondrial solute carrier. Mediates the reversible, electroneutral exchange of Mg-ATP or Mg-ADP against phosphate ions, catalyzing the net uptake or efflux of adenine nucleotides across the mitochondrial inner membrane. Nucleotide transport is inactive when cytosolic calcium levels are low, and is activated by an increase in cytosolic calcium levels. May play a role in protecting cells against oxidative stress-induced cell death, probably by promoting the formation溶质载体家族25成员24抗体 of calcium-phosphate precipitates in the mitochondrial matrix, and thereby buffering calcium levels in the mitochondrial matrix. Tissue Specificity: Present in various cell lines (at protein level). Expressed in all tissues tested. Highly expressed in testis, 溶质载体家族25成员24抗体expressed at intermediate level in small intestine and pancreas, and weakly expressed in kidney, spleen, liver, skeletal muscle and heart. Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family. Database links: Entrez Gene: 29957 Human Omim: 608744 Human SwissProt: Q6NUK1 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶质载体家族25成员24抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 转运蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid