RALGPS2蛋白抗体
规格:1mg/1ml
英文名: RALGPS2
别名: dJ595C2.1; FLJ10244; FLJ25604; KIAA0351; Ral A exchange factor RalGPS2; Ral GEF with PH domain and SH3 binding motif 2; RALGPS 2; ras-specific guanine nucleotide-releasing factor RalGPS2.
分子量: 65kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RALGPS2
交叉反应:Human, Mouse, Rat, Chicken, Chimpanzee,
细胞定位:细胞浆 细胞膜
RALGPS2蛋白抗体产品介绍:background: RalGPS2 (Ral GEF with PH domain and SH3 binding motif 2) is a guanine nucleotide exchange factor for RalA GTPase. It is expressed in testis and brain. Function: Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity). Subunit: Interacts with the SH3 domains of GRB2 and PLCG1. Interacts with RALA. Subcellular Location: Cell Membrane and Cytoplasmic. Associates with membranes through the PH domain. DISEASE: RALGPS2 is a potential candidate gene for susceptibility to Alzheimer disease linked to RALGPS2蛋白抗体1q24. Database links: Entrez Gene: 424429 Chicken Entrez Gene: 457549 Chimpanzee Entrez Gene: 100052879 Horse Entrez Gene: 55103 Human Entrez Gene: 78255 Mouse Entrez Gene: 304887 Rat Entrez Gene: 717165 Rhesus monkey Entrez Gene: 779506 Xenopus tropicalis Entrez Gene: 393446 Zebrafish SwissProt: Q5ZJK0 Chicken SwissProt: Q4R7W3 Cynomolgus Monkey SwissProt: Q86X27 Human SwissProt: RALGPS2蛋白抗体Q9ERD6 Mouse Unigene: 632485 Human Unigene: 28376 Mouse Unigene: 224486 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RALGPS2蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid