SH3D19抗体
规格：1mg/1ml
英文名： SH3D19
别名： ADAM-binding protein Eve-1; EBP; EEN-binding protein; SH3 domain protein D19; SH3 domain-containing protein 19; SH319_HUMAN; Sh3d19; SH3D19 protein.
分子量： 86kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SH3D19
交叉反应：Human, Mouse, Dog, Cow, Horse, Sheep,
细胞定位：细胞核 细胞浆
SH3D19抗体产品介绍：background: This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] Function: May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Subcellular Location: Cytoplasm. Nucleus. Is recruited to the nucleus by SH3D19抗体the MLL-EEN fusion protein;. Tissue Specificity: Widely expressed with highest levels in heart, skeletal muscle, kidney, liver, placenta, small intestine and lung. Expressed at low levels in colon, thymus, spleen and leukocytes. Similarity: Contains 5 SH3 domains. Gene ID: SH3D19抗体152503 Database links: Entrez Gene: 482645 Dog Entrez Gene: 100727056 Guinea pig Entrez Gene: 100062398 Horse Entrez Gene: 152503 Human Entrez Gene: 100518918 Pig Entrez Gene: 100353862 Rabbit Omim: 608674 Human SwissProt: Q5HYK7 Human Unigene: 728240 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SH3D19抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid