G蛋白结合蛋白RAB相互作用蛋白抗体
规格：1mg/1ml
英文名： RAB11FIP1
别名： FLJ22524; FLJ22622; HGNC:30265; MGC78448; No Rab11 binding protein 1A; NOEL1A; Rab coupling protein; Rab effector protein; Rab interacting recycling protein; Rab-coupling protein; RAB11 family interac
分子量： 65kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RAB11FIP
交叉反应：Human, Mouse, Rat,
细胞定位：
G蛋白结合蛋白RAB相互作用蛋白抗体产品介绍：background: This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013] Function: A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking G蛋白结合蛋白RAB相互作用蛋白抗体along the phagocytic pathway and in phagocytosis. Subcellular Location: Recycling endosome. Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC) and Cytoplasmic vesicle, phagosome membrane. Membrane-bound (isoform 2). Colocalizes with Rab11A at phagosomes (isoform 2). Tissue Specificity: Isoform 2 is expressed in brain, heart, testis, lung, spleen, ovary and small intestine. Similarity: Contains 1 C2 domain. Contains 1 FIP-RBD domain. Database links: Entrez Gene: 80223 Human Entrez Gene: 75767G蛋白结合蛋白RAB相互作用蛋白抗体 Mouse Entrez Gene: 498650 Rat Omim: 608737 Human SwissProt: Q6WKZ4 Human SwissProt: Q9D620 Mouse SwissProt: Q3B7T9 Rat Unigene: 191179 Human Unigene: 205335 Mouse Unigene: 49288 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白结合蛋白RAB相互作用蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid