PYDC2蛋白抗体
规格:1mg/1ml
英文名: PYDC2
别名:
分子量: 11kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PYDC2
交叉反应:Human,
PYDC2蛋白抗体细胞定位:细胞核 细胞浆
产品介绍:Function: May play a role in innate immunity by disrupting the interaction between PYCARD and NLRP3, thereby regulating the NLRP3 inflammasome (PubMed:17339483, PubMed:17178784). May also inhibit NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA (PubMed:17339483, PubMed:24871464). Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: PYDC2蛋白抗体Predominantly expressed in peripheral blood. Weakly expressed in testis. Similarity:PYDC2蛋白抗体 Contains 1 DAPIN domain. Database links: Entrez Gene: 152138 Human SwissProt: Q56P42 Human Unigene: 690618 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PYDC2蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid