组氨酸酸性磷酸酶结构域蛋白1抗体
规格:1mg/1ml
英文名: PPIP5K2/HISPPD1
别名: Diphosphoinositol pentakisphosphate kinase 2; HISPPD1; Histidine acid phosphatase domain containing 1; Histidine acid phosphatase domain containing protein 1; Histidine acid phosphatase domain-contain
分子量: 138kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PPIP5K2/
交叉反应:Human, Mouse, Rat, Rabbit,
细胞定位:细胞浆
组氨酸酸性磷酸酶结构域蛋白1抗体产品介绍:background: Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]).[supplied by OMIM, Mar 2008] Function: Bifunctional inositol kinase that catalyzes the formation of diphosphoinositol pentakisphosphate (InsP7 or PP-InsP5) and bi-diphosphoinositol tetrakisphosphate (InsP8 or PP2-InsP4). Converts inositolitol hexakisphosphate (InsP6) to InsP7. Also able to convert InsP7 to InsP8. Probably specifically mediates the formation of 4PP-InsP5 and 6PP-InsP5 InsP7 isomers but not组氨酸酸性磷酸酶结构域蛋白1抗体 of 5PP-IP5 InsP7 isomer. Subcellular Location: Cytoplasm > cytosol. Tissue Specificity: Belongs to the histidine acid phosphatase family. VIP1 subfamily. Similarity: Belongs to the histidine acid phosphatase family. VIP1 subfamily. Database links: Entrez Gene: 101091503 Cat Entrez Gene: 780855 Cow Entrez Gene: 488883 Dog Entrez Gene: 100712709 Guinea pig Entrez Gene: 100064726 Horse Entrez 组氨酸酸性磷酸酶结构域蛋白1抗体Gene: 23262 Human Entrez Gene: 227399 Mouse Entrez Gene: 501194 Rat Omim: 611648 Human SwissProt: O43314 Human SwissProt: Q6ZQB6 Mouse Unigene: 212046 Human Unigene: 220817 Mouse Unigene: 417682 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
组氨酸酸性磷酸酶结构域蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid