泛素特异性蛋白酶52抗体
规格：1mg/1ml
英文名： USP52/Pan2
别名： hPan2; Inactive ubiquitin carboxyl terminal hydrolase 52; Inactive ubiquitin carboxyl-terminal hydrolase 52; KIAA0710; PAB dependent poly(A) specific ribonuclease subunit 2; PAB-dependent poly(A)-spec
分子量： 135kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human USP52/Pa
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：细胞核 细胞浆
泛素特异性蛋白酶52抗体产品介绍：background: This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] Function: Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, shortens poly(A) tails of RNA when the poly(A) stretch is bound by polyadenylate-binding protein. Subcellular Location: Cytoplasm. Nucleus. Shuttles between nucleus and cytoplasm. Similarity: Belongs to泛素特异性蛋白酶52抗体 the peptidase C19 family. PAN2 subfamily. Contains 1 exonuclease domain. Database links: Entrez Gene: 9924 Human Entrez Gene: 103135 Mouse Entrez Gene: 408200 Rat SwissProt: Q504Q3 Human SwissProt: Q8BGF7 Mouse SwissProt: Q6IE70 Rat Unigene: 273397 Human Unigene: 244183 Mouse Unigene: 9091 Rat Important Note: This product as supplied is intended for research use only, not for use in human, 泛素特异性蛋白酶52抗体therapeutic or diagnostic applications.
泛素特异性蛋白酶52抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 转录调节因子 表观遗传学 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid