多聚腺苷酸结合蛋白相互作用蛋白2抗体
规格：1mg/1ml
英文名： PAIP2
别名： PABP-interacting protein 2; PAIP-2; PAIP2; PAIP2_HUMAN; poly(A) binding protein interacting protein 2; Poly(A)-binding protein-interacting protein 2; Polyadenylate-binding protein-interacting protein
分子量： 15kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PAIP2
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
多聚腺苷酸结合蛋白相互作用蛋白2抗体产品介绍：Function: Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. Subunit: Interacts with the RRM1-RRM2 and C-terminus regions of PABPC1 in a 1:1 stoichiometry. Interacts with EIF4A.多聚腺苷酸结合蛋白相互作用蛋白2抗体 Subcellular Location: Cytoplasm. Similarity: Belongs to the PAIP2 family. Database links: Entrez Gene: 416187 Chicken Entrez Gene: 536619 Cow Entrez Gene: 51247 Human Entrez Gene: 67869 Mouse Entrez Gene: 361309 Rat Omim: 605604 Human SwissProt: Q5ZJS6 Chicken SwissProt: Q3ZC67 Cow SwissProt: Q9BPZ3 Human SwissProt: Q9D6V8 Mouse SwissProt: Q6AXZ0 Rat Unigene: 396644多聚腺苷酸结合蛋白相互作用蛋白2抗体 Human Unigene: 126534 Mouse Unigene: 1073 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多聚腺苷酸结合蛋白相互作用蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid