多聚腺苷酸结合蛋白相互作用蛋白1抗体
规格：1mg/1ml
英文名： PAIP1
别名： MGC12360; OTTHUMP00000221601; OTTMUSP00000026880; PABC1 interacting protein 1; PABP interacting protein 1; PABP-interacting protein 1; PAIP 1; PAIP-1; Paip1; PAIP1_HUMAN; Poly(A) binding protein inter
分子量： 54kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PAIP1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
多聚腺苷酸结合蛋白相互作用蛋白1抗体产品介绍：background: The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008] Function: Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other 多聚腺苷酸结合蛋白相互作用蛋白1抗体RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Subcellular Location: Cytoplasm. Similarity: Contains 1 MIF4G domain. Database links: Entrez Gene: 510246 Cow Entrez Gene: 10605 Human Entrez Gene: 218693 Mouse Entrez Gene: 365684 Rat Omim: 605184 多聚腺苷酸结合蛋白相互作用蛋白1抗体Human SwissProt: Q9H074 Human SwissProt: Q8VE62 Mouse Unigene: 482038 Human Unigene: 132584 Mouse Unigene: 9450 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多聚腺苷酸结合蛋白相互作用蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid