钠钙交换蛋白3抗体
规格：1mg/1ml
英文名： NCX3
别名： AW742262; MGC90626; Na(+)/Ca(2+)-exchange protein 3; Na+/Ca2+ exchange protein 3; Na+/Ca2+ exchanger 3; NAC3_HUMAN; NCX3; SCL8A3; Sodium calcium exchanger form 3; Sodium/calcium exchanger 3; Sodium/ca
分子量： 100kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NCX3
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞膜
钠钙交换蛋白3抗体产品介绍：background: SLC8A3 is a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Function: Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity). Subcellular 钠钙交换蛋白3抗体Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Isoform 2 is expressed in brain and skeletal muscle. Isoform 3 is expressed in excitable cells of brain, retina and skeletal muscle. Isoform 4 is expressed in skeletal muscle. Similarity: Belongs to the sodium/potassium/calcium exchangerv family. SLC8 subfamily. Contains 2 Calx-beta domains. Gene ID: 6547 Database links: Entrez Gene: 6547 Human Entrez Gene: 110893 Mouse Entrez Gene: 140448 Rat Omim: 607991 Human SwissProt: P57103 Human SwissProt: P70549 Rat Unigene: 337696 Human钠钙交换蛋白3抗体 Unigene: 443748 Mouse Unigene: 67030 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 钠钙交换蛋白又称钠钙交换体，有三种同分异构体,即NCX1、NCX2和NCX3。3型Na-Ca交换蛋白-NCX3, 主要在脑组织表达，分布与胞浆及胞膜。
钠钙交换蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 神经生物学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid