细胞色素P450 2C19抗体
规格：1mg/1ml
英文名： CYP2C19
别名： AI266900; CYP2C; CYP2C19; CYP2C37; CYP2C50; Cyp2c54; CYP450-2C; CPCJ; CYPIIC17; CYPIIC19; EG404195; LOC293989; MGC109053; P450-11A; P450C2C; P450IIC19; CP2CJ_HUMAN Cytochrome P450 2C19; R)-limonene 6-
分子量： 56kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CYP2C19
交叉反应：Human,
细胞定位：细胞浆 细胞膜
细胞色素P450 2C19抗体产品介绍：background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq] Function: Responsible for the metabolism of a number of therapeutic agents such as the 细胞色素P450 2C19抗体anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, Subcellular Location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane 细胞色素P450 2C19抗体protein. Similarity: Belongs to the cytochrome P450 family. Gene ID: 1557 Database links: Entrez Gene: 1557 Human Omim: 124020 Human SwissProt: P33261 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞色素P450 2C19抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid