6-磷酸果糖激酶C抗体
规格：1mg/1ml
英文名： PFKP
别名： 1200015H23Rik; 6 phosphofructokinase type C; 6 phosphofructokinase, platelet type; 6-phosphofructokinase; 6-phosphofructokinase type C; 9330125N24Rik; FLJ40226; K6PP; K6PP_HUMAN; MGC105718; PFK C; PFK
分子量： 86kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PFKP
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
6-磷酸果糖激酶C抗体产品介绍：background: The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM, Mar 2008] Function: Catalyzes the phosphorylation of D-fructose 6-phosphate 6-磷酸果糖激酶C抗体to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. Subunit: Homo- and heterotetramers. Muscle is M4, liver is L4, and red cell is M3L, M2L2, or ML3. A subunit composition with a higher proportion of platelet type subunits is found in platelets, brain and fibroblasts. Subcellular Location: Cytoplasm. Tissue Specificity: GlcNAcylation decreases enzyme activity. Similarity: Belongs to the phosphofructokinase family. Two domains subfamily. Gene ID: 5214 Database links: Entrez Gene: 5214 Human Entrez Gene: 56421 Mouse Entrez Gene: 6-磷酸果糖激酶C抗体60416 Rat Omim: 171840 Human SwissProt: Q01813 Human SwissProt: Q9WUA3 Mouse SwissProt: P47860 Rat Unigene: 26010 Human Unigene: 273874 Mouse Unigene: 2278 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
6-磷酸果糖激酶C抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid