红细胞生成素抗体
规格：1mg/1ml
英文名： EPO
别名： Erythropoietin precursor; EP; EPO alpha; EPO; Epoetin; Erythropoetin; Erythropoietin; MGC138142; EPO_HUMAN.
分子量： 28kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
免疫原：KLH conjugated synthetic peptide derived from human EPO
交叉反应：Human, Mouse, Pig, Cow, Sheep,
细胞定位：分泌型蛋白
红细胞生成素抗体产品介绍：background: Human erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of ***** mammals and by liver of fetal or neonatal mammals. Function: Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Subcellular Location: Secreted. Tissue Specificity: Produced by kidney or liver of ***** mammals and by liver of fetal or neonatal mammals. DISEASE: Microvascular complications of diabetes 2 (MVCD2) [MIM:612623]: Pathological conditions that develop in numerous红细胞生成素抗体 tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic *****s. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. Similarity: Belongs to the EPO/TPO family. Gene ID: 2056 Database links: Entrez Gene: 2056 Human Entrez红细胞生成素抗体 Gene: 13856 Mouse Entrez Gene: 24335 Rat Omim: 133170 Human SwissProt: P01588 Human SwissProt: P07321 Mouse SwissProt: P29676 Rat Unigene: 2303 Human Unigene: 349116 Mouse Unigene: 11365 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
红细胞生成素抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 免疫学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid