转录因子COUP1抗体
规格：1mg/1ml
英文名： COUP-TF1
别名： Chicken ovalbumin upstream promoter 1; chicken ovalbumin upstream promoter; COT1_HUMAN; COUP transcription factor 1; COUP transcription factor I; COUP-TF I; COUP TF1; EAR-3; EAR3; ERBAL3; NR2F1; Nucle
分子量： 46kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human COUP-TF1
交叉反应：Human, Mouse, Rat, Pig, Cow, Sheep,
细胞定位：细胞核
转录因子COUP1抗体产品介绍：background: COUP transcription factors have been cloned in several species and identified as orphan members of the steroid/thyroid hormone receptor superfamily. COUP-TFI (also designated COUP or EAR-3) and ARP-1 (also designated COUP-TFII) exhibit highly regulated and overlapping expression in most tissues. COUP-TFs are highly expressed in the developing and central nervous system, suggesting that these factors may be important in neural development and differentiation. COUP-TFs can compete for binding to response elements which are common to other members of this family, including RAR, RXR, PPAR, HNF-4, VDR and TR. They have been shown to act as negative regulators as well as initiators of transcription. Function: Coup (chicken ovalbumin upstream promoter) transcription factor binds转录因子COUP1抗体 to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. Represses transcriptional activity of LHCG. Subunit: Binds DNA as dimer; homodimer and probable heterodimer with NR2F6. Interacts with COPS2. Subcellular Location: Nucleus. Similarity: Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. Gene ID: 7025 Database links: Entrez Gene: 7025 Human Entrez Gene: 13865转录因子COUP1抗体 Mouse Entrez Gene: 81808 Rat Omim: 132890 Human SwissProt: P10589 Human SwissProt: Q60632 Mouse Unigene: 519445 Human Unigene: 439653 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子COUP1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞粘附分子 细胞外基质 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid