桥粒糖蛋白1抗体
规格：1mg/1ml
英文名： Desmocollin 1
别名： Cadherin family member 1; CDHF1; Desmocollin1; Desmosomal glycoprotein 2/3; DG2/DG3; DSC 1; DSC1; DSC1_HUMAN.
分子量： 85kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Desmocol
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
桥粒糖蛋白1抗体产品介绍：background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] Function: Component of intercellular桥粒糖蛋白1抗体 desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome. Tissue Specificity: Strongly expressed in epidermis, less in lymph node and tongue. Similarity: Contains 5 cadherin domains. Gene ID: 1823 Database links: Entrez 桥粒糖蛋白1抗体Gene: 1823 Human Entrez Gene: 13505 Mouse Entrez Gene: 291759 Rat Omim: 125643 Human SwissProt: Q08554 Human SwissProt: P55849 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
桥粒糖蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 转录调节因子 细胞粘附分子 细胞表面分子 糖蛋白 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid