生长素/肥胖抑制素前**原抗体
规格：1mg/1ml
英文名： Obestatin
别名： Appetite-regulating hormone; ghrelin/obestatin preprohormone; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide; MTLRP; obestatin 13; Obestatin 23; obestatin-13; O
分子量： 2.5kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Obestati
交叉反应：Human,
细胞定位：分泌型蛋白
生长素/肥胖抑制素前**原抗体产品介绍：background: This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent生长素/肥胖抑制素前**原抗体 reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014] Subcellular Location: Secreted. Gene ID: 51738 生长素/肥胖抑制素前**原抗体Database links: Entrez Gene: 51738 Human Omim: 605353 Human SwissProt: Q9UBU3 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
生长素/肥胖抑制素前**原抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid