富含半胱氨酸运动神经元蛋白1抗体
规格：1mg/1ml
英文名： CRIM1
别名： Cysteine-rich motor neuron 1 protein; CRIM-1; Cysteine-rich repeat-containing protein S52; Processed cysteine-rich motor neuron 1protein; CRIM 1; CRIM1; Cysteine rich motor neuron 1 protein; Cysteine
分子量： 110kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse CRIM1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜 分泌型蛋白
富含半胱氨酸运动神经元蛋白1抗体产品介绍：background: CRIM1 interacts with BMP4 (bone morphogenic protein 4) and BMP7 and modulates BMP activity by affecting their processing and delivery to the cell surface. By interacting with growth factors implicated in motor neuron differentiation and survival, it may play a role in CNS development. It may also play a role in capillary formation and maintenance during angiogenesis. Function: May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to富含半胱氨酸运动神经元蛋白1抗体 the cell surface. Subcellular Location: Secreted and Cell membrane. Tissue Specificity: Expressed in pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver and small intestine. Expressed in blood vessels (at protein level). Post-translational modifications: N-glycosylated. Similarity: Contains 4 antistasin-like domains. Contains 1 IGFBP N-terminal domain. Contains 6 VWFC domains.富含半胱氨酸运动神经元蛋白1抗体 Gene ID: 50766 Database links: Entrez Gene: 51232 Human Entrez Gene: 50766 Mouse Omim: 606189 Human SwissProt: Q9NZV1 Human SwissProt: Q9JLL0 Mouse Unigene: 699247 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
富含半胱氨酸运动神经元蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 染色质和核信号 神经生物学 信号转导 血管内皮细胞 细胞骨架 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid