CD43抗体
规格：1mg/1ml
英文名： CD43
别名： CD 43; CD43; CD43 antigen; Galactoglycoprotein; Galactoglycoprotein; GALGP; GPL 115; GPL115; Human gene for sialophorin; Leucocyte sialoglycoprotein; Leucocyte sialoglycoprotein; LEUK_HUMAN; Leukocyte
分子量： 38kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD43
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
CD43抗体产品介绍：background: The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. [provided by RefSeq, Sep 2011]. Function: One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response. Subunit: Interacts with HIPK2 via the cytoplasmic domain. Interacts with RDX.CD43抗体 Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Cell surface ofCD43抗体 thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas. Post-translational modifications: Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures. Gene ID: 6693 Database links: Entrez Gene: 6693 Human Entrez Gene: 20737 Mouse Omim: 182160 Human SwissProt: P16150 Human SwissProt: P15702 Mouse Unigene: 632188 Human Unigene: 283714 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD43抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 干细胞 细胞类型标志物 **细胞 t-**细胞 b-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid