喹啉酸磷酸核糖基转移酶抗体
规格：1mg/1ml
英文名： QPRT/QAPRTase
别名： NADC_HUMAN; Nicotinate nucleotide pyrophosphorylase (carboxylating); Nicotinate-nucleotide pyrophosphorylase [carboxylating]; QAPRTase; QPRT; QPRTase; Quinolinate phosphoribosyltransferase [decarboxyl
分子量： 31kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human QPRT/QAP
交叉反应：Human, Mouse, Rat, Dog, Cow, Sheep,
细胞定位：细胞浆
喹啉酸磷酸核糖基转移酶抗体产品介绍：background: Quinolinate phosphoribosyltransferase (QPRTase) is a major enzyme in the catabolism of quinolinate. Quinolinate is an intermediate in the tryptophan-nicotinamide adenine dinucleotide (NAD) pathway, leading to the production of nicotinic acid, carbon dioxide, and pyrophosphate. Catabolism of quinolinate is vital due to the quinolinate’s neurotoxicity. Increased levels of quinolinate have been linked to neurodegenerative symptoms associated with meningitis and AIDS. QAPRTase has a seven-stranded alpha/beta-barrel domain which is similar in structure to the eight-stranded alpha/beta-barrel enzymes. The protein possesses a novel fold in comparison to other members of the PRTase family. This fold comprises a structure combining two domains. The structure is part alpha/beta 喹啉酸磷酸核糖基转移酶抗体barrel-like domain, and part alpha/beta N-terminal domain. Function: Involved in the catabolism of quinolinic acid (QA). Subunit: Hexamer formed by 3 homodimers. Similarity: Belongs to the nadC/modD family. Gene ID: 23475 Database links: Entrez Gene: 614254 Cow Entrez Gene: 607664 Dog Entrez Gene: 100727900 Guinea pig Entrez Gene: 100065768 Horse Entrez Gene: 23475 Human 喹啉酸磷酸核糖基转移酶抗体Entrez Gene: 100406642 Marmoset (common) Omim: 606248 Human SwissProt: Q3T063 Cow SwissProt: Q15274 Human Unigene: 513484 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
喹啉酸磷酸核糖基转移酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 Alzheimer's
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid